Farmers of the Peruvian Andesmake use of seed-size variation as a source offlexibility in the production of ``nativecommercial'' farmer varieties of Andeanpotatoes and ulluco. In a case study of easternCuzco, the use of varied sizes of seed tubers isfound to underpin versatile farm strategiessuited to partial commercialization (combinedwith on-farm consumption and the next season'sseed). Use of seed-size variation also providesadaptation to diverse soil-moistureenvironments. The importance and widespread useof seed-size variation among farmers isdemonstrated in the emphasis and consistency oflinguistic expressions about (...) this trait. Smalland small-medium seed is typically sown in thecommunity's ``Hill'' unit of sub-humid,upper-elevation agriculture. Seed tubers ofmedium-size and larger are needed fordrought-stressed locales in lower-elevationlandscape units. Farm-level preferences for theseed-size of tubers also suggest potentialrelations to resource endowments of farmhouseholds and gender-related management,although these tendencies were notstatistically significant in the study. Anintra-varietal, landscape-environmentalperspective on seed-size management, whichincludes an emphasis on within-fieldversatility, helps to strengthen the researchsupport of local seed production in policiesand programs aiming for in situagrobiodiversity conservation, marketingcapacity, and food security. (shrink)

Globalization offers a mix of new trajectories for agriculture, livelihoods, resource use, and environmental conservation. The papers in this issue share elements that advance our understanding of these new trajectories. The shared elements suggest an approach that places stress on: (i) the common ground of theoretical concepts (local-global interactions), methodologies (case study design), and analytical frameworks (spatio-temporal emphasis); (ii) farm-level economic diversification and the dynamics of agricultural intensification-disintensification; (iii) the pervasive role of agricultural as well as environmental institutions, organizations, and (...) governance issues; (iv) the ‹agency of nature’ that blends the roles of non-human organisms and the cultural and social practices of people both at the local scale and beyond; (v) the framing of sustainability initiatives and outcomes through the perspective of historical change; (vi)␣spatial environmental dynamics of the ‹new geographics of environmental conservation’ that impact agriculture, food production, and resource management; and (vii) successful and promising policies, projects, and developments mapping out possible spaces of hope for agricultural sustainability, aquitable development, and food security. The adoption and application of these elements is successful also in avoiding the tendency toward just-so accounts or overly simplified stories of agrarian and environment successes amid the often grim realities of globalization and its impacts. (shrink)

Cell biologists, including those seeking molecular mechanistic explanations of cellular phenomena, frequently rely on experimental strategies focused on identifying the cellular context relevant to their investigations. We suggest that such practices can be understood as a guided decomposition strategy, where molecular explanations of phenomena are defined in relation to natural contextual (cell) boundaries. This “top-down” strategy contrasts with “bottom-up” reductionist approaches where well-defined molecular structures and activities are orphaned by their displacement from actual biological functions. We focus on the central (...) role of microscopic imaging in cell biology to uncover possible constraints on the system. We show how identified constraints are used heuristically to limit possible mechanistic explanations to those that are biologically meaningful. Historical examples of this process described here include discovery of the mechanism of oxidative phosphorylation in mitochondria, molecular explanation of the first steps in protein secretion, and identification of molecular motors. We suggest that these instances are examples of a form of downward causation or, more specifically, constraining relations, where higher-level structures and variables delimit and enable lower-level system states. The guided decomposition strategy in our historical cases illustrates the irreducibility of experimentally identified constraints in explaining biological activities of cells. Rather than viewing decomposition and recomposition as separate epistemic activities, we contend that they need to be iteratively integrated to account for the ontological complexity of multi-level systems. (shrink)

In the 1950s and 1960s, the search for the mechanism of oxidative phosphorylation by biochemists paralleled the description of mitochondrial form by George Palade and Fritiof Sjöstrand using electron microscopy. This paper explores the extent to which biochemists studying oxidative phosphorylation took mitochondrial form into account in the formulation of hypotheses, design of experiments, and interpretation of results. By examining experimental approaches employed by the biochemists studying oxidative phosphorylation, and their interactions with Palade, I suggest that use of mitochondrial form (...) as a guide to experimentation and interpretation varied considerably among investigators. Most notably, Peter Mitchell, whose chemiosmotic hypothesis was ultimately the basis of the correct mechanism of oxidative phosphorylation, incorporated crucial aspects of mitochondrial form into his model that others failed to recognize. I discuss these historical observations in terms of the background and training of the biochemists, as well as a proposed heuristic of form, whose use may increase the possibility that biologically meaningful molecular mechanisms will be discovered. (shrink)

Present-day speculation on extraterrestrial intelligence, taking its cue from a number of programmes currently "listening" for electro-magnetic signals from space, have a prehistory dating back to the immediate aftermath of the Copernican Revolution. Throughout the centuries of the Early Modern Period, it was not only theological but also more or less secular philosophical concerns that informed the hopes and the fears that writers of all stripes associated with the tentative notion that "We are not alone." It was not until the (...) "Romantic" period, around 1800, that a reaction set in: as Goethe put it, there is also a universe within us-one worthier of our attention than the cosmos. (shrink)

Enrique Dussel's writings span the theology of liberation, critiques of discourse ethics, evaluations of Marx, Levinas, Habermas, and others, but most importantly, the development of a philosophy written from the underside of Eurocentric modernist teleologies, an ethics of the impoverished, and the articulation of a unique Latin American theoretical perspective. This anthology of original articles by U.S. philosophers elucidating Dussel's thought, offers critical analyses from a variety of perspectives, including feminist ones. Also included is an essay by Dussel that responds (...) to these essays. (shrink)

The roles played by physics in the study of the life sciences have taken many forms over the past 100 years. Here we analyze how physics can be brought to bear on the contemporary study of morphogenesis, where new tissue-scale forms arise out of simpler, more homogenous, initial structures. We characterize how morphogenesis has been studied through reductionist approaches and discuss their limitations. We suggest that an alternative way of approaching morphogenesis that begins with a consideration of the whole may (...) also serve as a fruitful mode of scientific inquiry. Through historical analysis of concepts relevant for contemporary systems biology, we illustrate how physical thinking oriented toward the biological whole (“holistic biophysical thinking”) was exemplified in the biological theories presented earlier by D’Arcy Thompson (1860–1948) and Pere Alberch (1954–1998). We contrast the use of physics to develop the conceptual foundations of holistically oriented systems biology with the more prevalent contemporary use of physics that focuses on technological development and quantification, embedded within reductionist strategies. As an in-depth contemporary case study, we describe how in our research we have used holistic biophysical thinking to develop biological theories of vertebrate morphogenesis that account for and extend beyond genetic, molecular, and cellular processes. We propose a theory of skin development where _both_ molecular _and_ morphological patterns are orchestrated by emergent physical processes at the supracellular scale. We further posit that holistic biophysical thinking at the supracellular scale may advance theories of diseases such as cancer. (shrink)

Abstract: The State of Nature, Prehistory, and Mythmaking Karl Widerquist This chapter provide an overview of two books, in which Grant S. McCall and I name, define, and debunk the following false claims that still play important roles in contemporary political theories although they are not always defined and defended explicitly: 1. The Hobbesian hypothesis: sovereign states and/or the liberal private property rights system benefits everyone (or at least harms no one) relative to how well they could reasonably expect (...) to live in the state of nature—i.e. a society lacking one or both of these institutions. 2. The appropriation hypothesis: private property in the form of liberal ownership rights develops naturally while collective, communal, common, or government-held property rights systems do not. 3. The natural inequality hypothesis: inequality is natural and inevitable, i.e. economic, social, and/or political equality cannot exist and/or cannot be created without a significant loss in negative freedom. 4. The market-freedom hypothesis: a market economy (and/or capitalism) is more consistent with negative freedom than any other economic system. The third and fourth of these claims are not obviously claims about prehistoric or small-scale societies, but they are universal claims about all societies and so they include claims about even the most remote and distant societies from contemporary thinking. (shrink)

The technique of covers is now well established in semigroup theory. The idea is, given a semigroup S, to find a semigroup having a better understood structure than that of S, and an onto morphism of a specific kind from to S. With the right conditions on , the behaviour of S is closely linked to that of . If S is finite one aims to choose a finite . The celebrated results for inverse semigroups of McAlister in the 1970s (...) form the flagship of this theory.Weakly left quasi-ample semigroups form a quasivariety (of algebras of type(2, 1)), properly containing the classes of groups, and of inverse, left ample, and weakly left ample semigroups. We show how the existence of finite proper covers for semigroups in this quasivariety is a consequence of Ashs powerful theorem for pointlike sets. Our approach is to obtain a cover of a weakly left quasi-ample semigroup S as a subalgebra of S × G, where G is a group. It follows immediately from the fact that weakly left quasi-ample semigroups form a quasivariety, that is weakly left quasi-ample. We can then specialise our covering results to the quasivarieties of weakly left ample, and left ample semigroups. The latter have natural representations as (2, 1)-subalgebras of partial (one-one) transformations, where the unary operation takes a transformation to the identity map in the domain of . In the final part of this paper we consider representations of weakly left quasi-ample semigroups. (shrink)

In 1935 geneticist Nikolai Timoféeff-Ressovsky, radiation physicist Karl G. Zimmer, and quantum physicist Max Delbrück published “On the Nature of Gene Mutation and Gene Structure,” known subsequently as the “Three-Man Paper.” This seminal paper advanced work on the physical exploration of the structure of the gene through radiation physics and suggested ways in which physics could reveal definite information about gene structure, mutation, and action. Representing a new level of collaboration between physics and biology, it played an important role (...) in the birth of the new field of molecular biology. The paper’s results were popularized for a wide audience in the What is Life? lectures of physicist Erwin Schrödinger in 1944. Despite its historical impact on the biological sciences, the paper has remained largely inaccessible because it was only published in a short-lived German periodical. Creating a Physical Biology makes the Three Man Paper available in English for the first time. Brandon Fogel’s translation is accompanied by an introductory essay by Fogel and Phillip Sloan and a set of essays by leading historians and philosophers of biology that explore the context, contents, and subsequent influence of the paper, as well as its importance for the wider philosophical analysis of biological reductionism. (shrink)

A bracing, concise, and accessible overview of the entirety of Marx's thought, by a major figure of twentieth-century Western Marxism.

Microbiologists are transitioning from the study and characterization of individual strains or species to the profiling of whole microbiomes and microbial ecology. Equipped with high-throughput methods for studying the taxonomic and functional characteristics of diverse samples, they are just beginning to encounter the conceptual, theoretical, and experimental problems of comparing taxonomy to function, and extracting useful measures from such comparisons. Although still unresolved, these problems are well studied in macro-ecology and are reiterated here as an historical precautionary for microbial ecologists. (...) Beyond expected and unresolved terminological vagueness, we argue that assessments and comparisons of taxonomic and functional profiles in micro-ecology suffer from theoretically unresolvable arbitrariness and ambiguities. We divide these into problems of scale, individuation, and commensurability. We argue that there is no technically/theoretically “correct” scale, individuation, or comparison of taxonomy and function, but there are nonetheless better and worse methodologies for profiling. (shrink)

Rather than adopting a view of Fichte as a “proto-existentialist,” as some scholars have suggested, I instead aim to develop an account which articulates a fundamental existential structure which helps to elucidate and situate later notions of existential subjectivity by accounting for its condition of possibility. In this vein, existentialism not only articulates a certain kind of being in the world but a logical condition of the structure of subjectivity itself. I call this structuring condition existential logic, and locate it (...) in Fichte's Wissenschaftslehre. I develop the term existential logic instead of merely attributing to Fichte the term existential-ism or existentialist, insofar as I aim to locate an operative structure within the being who then becomes an existential subject for whom existential engagement is only then possible. The term existential logic suggests that the striving of the self both with and against the world—as existential phenomenology would have it—is a structure inherent within Fichte's logical deduction and formulation of the Absolute I. (shrink)

Karl Ameriks here collects his most important essays to provide a uniquely detailed and up-to-date analysis of Kant's main arguments in all three major areas of his work: theoretical philosophy (Critique of Pure Reason), practical philosophy (Critique of Practical Reason), and aesthetics (Critique of Judgment). Guiding the volume is Ameriks's belief that one cannot properly understand any one of these Critiques except in the context of the other two. The essays can be read individually, but read together they offer (...) a comprehensive guide to the main themes of the most influential of all modern philosophical systems. (shrink)

First Published in 2004. Lowith's study of Max Weber and Karl Marx is a key text in modem interpretations of the theme of alienation in Marxist theory and rationalisation in Weber's sociology. It remains the best short student introduction to the differences and comparisons between these essential thinkers. This new edition includes a Preface by Professor Bryan S. Turner which demonstrates the relevance of the book for contemporary sociology.

ABSTRACT Between the first two Critiques, Kant wrote what he called a “conjectural history” of the development of human freedom through a reading of Genesis. In the essay, reason itself is conceived of in terms of its “genesis,” and Kant primarily reads “Genesis” as an account of reason’s ascension or becoming. Just as humankind becomes itself through the Fall, so too does reason simultaneously come into its own. Adam indeed acts as a template for the conception of moral agency that (...) Kant will go on to develop in much more detail in the second critique. More significantly, however, as I argue below, the “genesis” and ascension of reason is only made possible through Eve’s covering up of herself. I argue that the act naturalizes both shame and clothing onto a feminine body conceived as un-reasonable. It is against this foil of unreason that reason is able to reach its own heights. I argue that Kant’s reading of Genesis in the “Conjectures” naturalizes women and clothing as superfluous: to humankind and to the ascent of reason alike. However, their function as the condition of possibility for Kant’s own system will show that they are anything but superfluous. Rather, they are essential. (shrink)

A selection of Karl Marx's most important writings are contained in this volume. It was designed as a companion to Elster's "An introduction to Karl Marx" but may be used alone.

What Sigmund Freud is to psychoanalysis, Max Weber is to sociology: the founding father, the primary source of idea, invention, and organization upon which the modern practice of the science is based. Karl Jaspers occupies an equally high place in the existentialist movement in philosophy. For many years, these two intellectual giants were close associates. These brilliant and eminently readable essays were written between 1920 and 1962, originally in German. Here they are available in English. Jaspers divides Weber's work (...) into three broad categories--philosophical, scientific, and political. He examines Weber's passionate devotion to the goal of purifying science of all passion, and specifically of making the social sciences an objective, value-free inquiry. He explores Weber's notion of the role of political leadership, and of the crisis of contemporary civilization as experienced in Germany. When one towering intellect writes about another, we enjoy insights into the minds of both. On Max Weber speaks to the philosopher, the sociologist, the political scientist, and the scholar, while it broadens the intellectual horizons of everyone concerned with deeper questions of mind, society, and the human condition.--From publisher description. (shrink)

We study some aspects of the emergence of _lógos_ from _xáos_ on a basal model of the universe using methods and techniques from algorithmic information and Ramsey theories. Thereby an intrinsic and unusual mixture of meaningful and spurious, emerging laws surfaces. The spurious, emergent laws abound, they can be found almost everywhere. In accord with the ancient Greek theogony one could say that _lógos_, the Gods and the laws of the universe, originate from “the void,„ or from _xáos_, a picture (...) which supports the unresolvable/irreducible lawless hypothesis. The analysis presented in this paper suggests that the “laws„ discovered in science correspond merely to syntactical correlations, are local and not universal. (shrink)

This study describes the results of experiments motivated by an attempt to understand spectral processing in the cerebral cortex (DeValois and DeValois, 1988; Pribram, 1971, 1991). This level of inquiry concerns processing within a restricted cortical area rather than that by which spatially separate circuits become synchronized during certain behavioral and experiential processes. We recorded neural responses for 55 locations in the somatosensory (barrel) cortex of the rat to various combinations of spatial frequency (texture) and temporal frequency stimulation of their (...) vibrissae. The recordings obtained from single and multi-unit bursts of spikes were mapped as surface distributions of local dendritic potentials. The distributions showed a variety of patterns that are asymmetric with respect to the spatial and temporal parameters of stimulation, and were, therefore, not simply reflecting whisker flick rate. Next, a simulation of our results showed that these surface distributions of local dendritic potentials can be described by Gabor-like functions much as in the visual system. The results provide support for a model of distributed cortical processing that imposes a physiologically derived frame (the limited extent of a dendritic patch) and an anatomically derived (axonal) sampling of the distributed process. This combination provides a complex Gabor wavelet that encodes phase, which is necessary to processing such details as edges and texture in a scene. The synchronization across cortical areas that make the Gabor wavelet processes within restricted cortical areas available to one another (the binding problem) proceed at a ''higher order'' level of integration. Both levels of distributed processing accomplish computation in the conjoint spacetime and spectral domain. (shrink)

This seminal contribution to Kant studies, originally published in 1982, was the first to present a thorough survey and evaluation of Kant's theory of mind. Ameriks focuses on Kant's discussion of the Paralogisms in the Critique of Pure Reason, and examines how the themes raised there are treated in the rest of Kant's writings. Ameriks demonstrates that Kant developed a theory of mind that is much more rationalistic and defensible than most interpreters have allowed.

Inhalt: K.-O. Apel: Vorwort - G. Calabro: Gesprach uber Hobbes mit Karl-Heinz Ilting - I. Grundfragen der praktischen Philosophie: H.-G. Gadamer: Die Gegenwart der sokratischen Frage in Aristoteles - P. Lorenzen: Politische Ethik - J. D'Hondt: Die Ethik und der Weltlauf - K.-O. Apel: Faktische Anerkennung oder einsehbar notwendige Anerkennung? - H. Schnadelbach: Rationalitat und Normativitat - F. W. Veauthier: Vom sozialen Verantwortungsapriori im phanomenologischen Denken - K. Lorenz: Der Antagonismus von Freiheit und Gerechtigkeit - P. Rohs: Moralische Praferenzen (...) - H. Hoppe: Normenbegrundung ohne naturalistischen Fehlschluss? - W. Kuhlmann: Solipsismus in Kants praktischer Philosophie und die Diskursethik - R. Maliandi: Anerkennung oder Argumentation? - L. H. Meyer: Anerkennung, Zumutbarkeit und Diskussion als praktische Prinzipien - A. Cortina: Substantielle Ethik oder wertfreie Verfahrensethik? - R. Zimmer: Der Selbstbezug des asthetischen Zeichens - II. Zur Geschichte der praktischen Philosophie: P. R. Franke: Zu einem Munzbildnis des Stoikers Chrysippos - V. Hosle: Recht und Geschichte bei Giambattista Vico - M. Riedel: Imputation der Handlung und Applikation des Sittengesetzes - A. Buha: Moral und Geschichte - C. Cesa: Zum Begriff des Praktischen bei Fichte - N. Bobbio: Hegel und das Recht - L. W. Beck: Reformation, Revolution und Restauration in Hegels politischer Philosophie - D. Losurdo: Moralisches Motiv und Primat der Politik bei Hegel - P. Becchi: Die Wurzeln der Ethik der Uberzeugung - R. Pozzo: 'Bourgeois' oder 'citoyen'? Zu Hegels Begriff der burgerlichen Gesellschaft - Die Veroffentlichungen K.-H. Iltings von P. Becchi - Personenregister - Sachregister. (shrink)

The article links Simone de Beauvoir’s phenomenology and Catherine A. MacKinnon’s feminist, Marxist, standpoint epistemology in virtue of their shared recognition that objectivity is sexed and gendered. This connection is supported by Beauvoir’s close alignment with Edmund Husserl, for whom the question of embodied difference was vital for generating an account of intersubjectivity and locating sex in the historical subject. The article concludes that a consideration of both the transcendental and immanence are central to Beauvoir’s feminist phenomenology and feminist politics (...) alike. (shrink)

With selections from Parts Two and Three, together with Marx's "Introduction to a Critique of Political Economy".

Do the partial order and ortholattice operations of a quantum logic correspond to the logical implication and connectives of classical logic? Rephrased, How far might a classical understanding of quantum mechanics be, in principle, possible? A celebrated result of Kochen and Specker answers the above question in the negative. However, this answer is just one among various possible ones, not all negative. It is our aim to discuss the above question in terms of mappings of quantum worlds into classical ones, (...) more specifically, in terms of embeddings of quantum logics into classical logics; depending upon the type of restrictions imposed on embeddings, the question may get negative or positive answers. (shrink)